Product Distribution

United Therapeutics has contracted with a limited distribution network of authorized specialty distributors and wholesalers. ASSIST works with Specialty Pharmacies (SPs) to help deliver your medicines. SPs can dispense United Therapeutics medicines to your home or to the office of your healthcare provider (HCP). SP nursing services will coordinate treatment with you when therapy begins.

Referral Process

  1. Referral is sent to SP
  1. SP collects missing information, performs benefit investigation
  1. SP calls qualifying patient with benefit summary, reviews financial assistance, refers to Hub if needed
  1. Hub reviews financial assistance needs, notifies SP of outcome
  1. SP calls patient, confirms coverage and assistance with patient and insurance, and schedules shipment and nursing services

Tyvaso Specialty Pharmacy Network


You can call ASSIST at 1-877-864-8437, Monday - Friday, 8:30am to 7:00pm ET or email ASSIST at

What is Tyvaso?

TYVASO (treprostinil) is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO. It is not known if TYVASO is safe and effective in children under 18 years of age.


Before you take TYVASO, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have bleeding problems
  • Are pregnant or plan to become pregnant. It is not known if TYVASO will harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if TYVASO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with TYVASO.

Tell your healthcare provider about all the medicines you take,including prescription and over-thecounter medicines, vitamins, and herbal supplements. TYVASO and other medicines may affect each other.

Especially tell your healthcare provider if you take:

  • Medicines used to treat high blood pressure or heart disease
  • Medicines that decrease blood clotting (anticoagulants)
  • Water pills (diuretics)
  • Gemfibrozil (Lopid®) or rifampin (Rimactane®, Rifadin®, Rifamate®, Rifater®)

What are the possible side effects of Tyvaso?

Tyvaso can cause serious side effects, including:

  • Low blood pressure (symptomatic hypotension). If you have low blood pressure, TYVASO may lower your blood pressure more.
  • Bleeding problems. TYVASO may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).

The most common side effects of TYVASO are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, and diarrhea. These are not all the possible side effects of TYVASO. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at or call 1-800-FDA-1088.

The risk information provided here is not comprehensive. To learn more about TYVASO, talk with your healthcare provider. Please see Full Prescribing Information, the TD-100 and TD-300 TYVASO® Inhalation System Instructions for Use manuals, and other additional information at or call 1-877-UNITHER (1-877-864-8437).