ASSIST® for ADCIRCA® (tadalafil)

Financial Support

Once your benefits have been verified, if you need financial assistance, you may qualify for one of the programs offered by United Therapeutics. Notify your Specialty Pharmacy (SP) when scheduling shipment or contact ASSIST directly.

Adcirca Co-Pay Assistance Card

If you have a commercial or private insurance plan, we offer a co-pay assistance card to help cover some of your out-of-pocket expenses.

Eligible patients on commercial/private insurance plans may pay as little as a $5 co-pay per prescription filled (program covers the difference in co-pay above $5 up to $800 monthly).

Terms and Conditions

*Patients must meet certain eligibility criteria to qualify for assistance. Patients receiving reimbursement under Medicare, Medicaid, VA, DoD (TRICARE), Indian Health Services, or similar federal or state programs, may not be eligible for some assistance. Some portion of this patient assistance may be administered by third-party patient assistance organizations. The Program is subject to additional state law restrictions. Patients residing in select states may not be eligible for the Program.

Patient Assistance Program (PAP)

United Therapeutics offers a free medication program for uninsured and underinsured patients who meet eligibility requirements.

Call ASSIST at 1-877-864-8437 to find out if you qualify for financial support.

Other financial support resources

There are independent Patient Assistance Programs* available that offer financial assistance to PAH patients in need. Known patient assistance programs that support PAH are listed below, in no particular order.

PAN Foundation

The Assistance Fund

Good Days

Patient Advocate Foundation

Patient Services, Inc.

*Independent patient assistance programs are fully separate from United Therapeutics, and United Therapeutics has no influence or control over these organizations. United Therapeutics has no control or insight into whether an independent PAP may or will approve an individual for assistance, and United Therapeutics does not receive any information about the status or decision of a grant application.

Questions?

If you have any questions about available financial support programs, contact ASSIST at 1-877-UNITHER (1-877-864-8437), Monday - Friday, 8:30 am to 7:00 pm ET.

Indication

ADCIRCA® (tadalafil) is a prescription medication used to treat pulmonary arterial hypertension (PAH) (WHO Group 1) to improve exercise ability. Studies establishing effectiveness included predominately patients with NYHA Functional Class II–III symptoms and etiologies of idiopathic or heritable PAH (61%) or PAH associated with connective tissue diseases (23%).

Important Safety Considerations for ADCIRCA® (tadalafil)

You should discuss all of your medical conditions and all medications with your healthcare provider before starting ADCIRCA

Do not take ADCIRCA if you take any medications that contain nitrates (often used for chest pain) or any guanylate cyclase stimulators (for example riociguat Adempas®), as the combination could cause a sudden, unsafe drop in blood pressure

Do not take ADCIRCA if you are allergic to tadalafil or any other ingredient in ADCIRCA

If you experience chest pain after taking ADCIRCA, contact your healthcare provider

ADCIRCA is a type of medication called a phosphodiesterase 5 inhibitor (PDE-5i). PDE-5is can cause blood vessels to widen, which may result in a decrease in blood pressure. If you have heart-disease or any problems with low blood pressure, tell your healthcare provider before taking ADCIRCA, as these conditions may be affected by the action of ADCIRCA

If you have ever had blockage in the veins of your lungs, known as pulmonary veno-occlusive disease (PVOD), ADCIRCA is not recommended for you

Taking ADCIRCA with alcohol, or blood pressure medications, such as alpha-blockers, may lower blood pressure and cause hypotension (light-headedness or fainting)

Do not take ADCIRCA if you are taking rifampin (an antibiotic for certain bacterial infections), or antifungal medications, such as ketoconazole and itraconazole. If you require treatment with both ADCIRCA and ritonavir (Norvir®) at the same time, your dose of ADCIRCA will need to be adjusted. Inform your healthcare provider if you have kidney or liver problems before taking ADCIRCA

ADCIRCA contains the same ingredient (tadalafil) as Cialis®, which is used to treat erectile dysfunction (ED, impotence) and the signs and symptoms of benign prostatic hyperplasia (BPH, enlarged prostate). If you are taking ADCIRCA, do not take Cialis or other PDE-5is

In rare cases, patients reported side effects such as decreased eyesight or loss of vision in one or both eyes (NAION), or sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness. If you experience any of these side effects after taking ADCIRCA, seek medical attention right away

In rare cases, men taking PDE-5is (including tadalafil) for erectile dysfunction reported side effects such as an erection lasting more than four hours. If you experience a prolonged erection, seek medical attention right away

The most common side effects of ADCIRCA are headache, muscle pain, getting red or hot in the face (flushing), nausea, pain in the arms, legs or back, upset stomach, stuffy or congested nose